Umzekelo, uqeqesho lobunzima luhlobo loxinzelelo. Iingcali ziya kuqinisekisa ukuba zenza i-micro-break in the fibers muscle ... kwaye ukuphilisa kwezi zilonda kubangela ukukhula nokuphuhliswa kwemizimba. Isiqinisekiso sokuqala esicinezelayo kwiimilinganiselo ezincinci sinokuba nemiphumo emihle kwizinto eziphilayo ezifunyenwe yi-pharmist waseJamani uHugo Schulz ekupheleni kwekhulu le-19. Wafumanisa ukuba imvubelo yaqhutyiswa ngakumbi xa idibanisa izinto ezinobuthi. Le nto yabizwa ngokuba yi "hormesis", ukusuka kwisiGrike mandulo "umdlalo, ukuvuselela". Ibonakala xa izinto eziphilayo zijongana nezilwanyana ezincinci zemitha, iityhefu, ukushisa okuphezulu kunye nezinye iziphumo ezinobungozi. Xa la manqanaba amancinci awanako ukwenza umonakalo omkhulu, sibona umfanekiso ochaseneyo: ukulungisa umonakalo omncinci, umzimba usebenze izixhobo zangaphakathi kwaye awuyikubuyiselwa kuphela umonakalo, kodwa kuphucula imeko yezicubu ezifaniswa nengqangi. Ukufumana iinkcukacha, jonga inqaku elithi "Impembelelo yokulala nokuxininisa kwimpilo yengqondo".
Impembelelo ye-Microdose
I-biogerontologist eyaziwayo emhlabeni uSuresh Rattan waseYunivesithi yaseAarhus (iDenmark) wacebisa ukusetyenziswa kwe-hormesis indlela yokulwa neenguqu ezinxulumene neminyaka. Wayebonakalisa ukuba ukuhamba ngokukhawuleza kumayeza amancinci okubangela uxinzelelo kukhuthaza ukuphendula okukhuselekileyo kweeseli kunye nokunciphisa inkqubo yokuguga. Ukuxinezeleka okunjalo kunokwenza iziphumo zomzimba (ukushisa okuphezulu, ukukhanya kwe-UV, imithwalo yemidlalo), ukutya okutya (ukutya okuncinci kwekhalori, ezinye iimveliso - i-calmeric, i-ginger kunye nabanye), iimeko zengqondo (umzekelo, uvuyo ngaphambi kokuba usebenze kuluntu). Ngo-2002, uRattan kunye noogxa bakhe bafunda umphumo wamanani amancinci okuxinwa kwi-protein kwi-aging fibroblasts (iiseli ezinoxanduva lokuvelisa i-collagen ne-elastin). Iingcali zenzululwazi zazinomdla kwenye yezinto ezibizwa ngokuba yi-protein zentsholongwane (HSP70), echaphazelekayo kwimpendulo yomzimba kwixinzelelo. Emva kokutshatyalaliswa kobushushu, izinga lale protein kwiseli landa, kunye nalo - ukumelana ne-ultraviolet kunye nezinto ezinobuthi. Iiseli eziguga zaba nzima kakhulu kwaye zinamandla.
Isigodlo sokuguga
Uphefumlelwe kukufumanisa, izazinzulu zama-laboratories zihlangene neqela lezinzululwazi ezikhokelwa nguRattan kwaye zenza iserum eguga i-anti-sting with a complex complex of ingredients, eyenza i-hormesom, i-hormomine. Kule meko, banegalelo ekuveliseni le protein kwaye ngaloo ndlela banqanda inkqubo yokuguga. Inkathazo ibandakanya ukukhishwa kwe-ginseng i-Sanchi ne-gipotaurin, efumaneka kwi-taurine-enye ye-amino acid ekhoyo emzimbeni womntu.
Impembelelo
Ekuhambeni kwezifundo, kwafunyanwa ukuba, emva kweeyure ezintandathu emva kokusetyenziswa kwe-serum, ukuveliswa kweprotein ye-HSP70 kwiseli kwanda ngo-24%. Uvavanyo lwekliniki lubonise ukuba ukukhusana kwesikhumba kwiimpembelelo zangaphandle emva kwenyanga yokusebenzisa i-serum kwanda ngo-3%. Enyanisweni, i-microstresses ibangela ukhenketho olunzima lweempendulo ezi-3 zokwenziwa kwezinto eziphilayo emzimbeni kwaye zisebenze kuquka iiprotheni zokutyhafaza. I-hormetins ayinceda nje iiseli ukuxhatshaza ukuguga, kodwa iyakwandisa ubude bomsebenzi osebenzayo weseli. Ininzi ehamba phambili ye-European dermatologists kunye ne-cosmetologists iyavuma ukuba ukusetyenziswa kweemveliso zesikhumba ezisekelwe ekuziqondeni ngokujulile kwimizimba yabantu kunye ne-biochemistry ekuqondeni iipropati zokubuyiselwa kwezicubu ze-biological zingenza impumelelo enkulu. Into ephambili kukuqinisekisa ukusetyenziswa kwabo okuchanekileyo. Ngoku siyazi ukuba yintoni impembelelo yokulala kunye noxinzelelo kwimpilo yolusu.